Recombinant full-length human OSR1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. O09-34G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| O09-34G-20 | 20 ug | $215 | |
| O09-34G-50 | 50 ug | $435 | |
| O09-34G-BULK | BULK | Contact Us |
Overview:
OSR1 is a member of the Ser/Thr family of protein kinases. OSR1 is activated by osmotic stresses and regulates the downstream protein kinase such as PAK1 in order to establish the sensor/signaling modules that initiate the cellular response to environmental stress (1). OSR1 can be phosphorylated by ATM or ATR during DNA damage process (2).
Gene Aliases:
OXSR1; KIAA1101
Genbank Number:
References:
1. Chen W. et al: Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily. J. Biol. Chem. 279:11129-11136(2004).
2. Matsuoka S. et al: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 316:1160-1166 (2007).
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~86 kDa
There are no related publications available for this product.
Cardiovascular Disease, Ser/Thr Kinases
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