Full-length recombinant human ACTR2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. A39-30G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| A39-30G-20 | 20 ug | $314 | |
| A39-30G-50 | 50 ug | $545 | |
| A39-30G-BULK | BULK | Contact Us |
Overview:
Belongs to the actin-related protein (Arp) superfamily whose primary sequences exhibited similarity, but not identity, to conventional actin. Along with Arp3 and 5 other proteins, ACTR2 makes up the evolutionary conserved Arp2/3 complex that was first identified in Acanthamoeba using profiling affinity chromatography and is an essential and ubiquitous component of the actin filament network. Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Gene Aliases:
ARP2
Genbank Number:
References:
1. Machesky LM, et al: 1994. Purification of a cortical actin complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose. J. Cell Biol. 127:107–15. 1994.
2. Schafer DA, et al: Actin-related proteins. Annu Rev Cell Dev Biol. 15:341-63. 1999
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~70 kDa
There are no related publications available for this product.
Cancer, Cellular Stress, Invasion/Metastasis
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