Recombinant full-length human LCMT2 protein was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. L322-30G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| L322-30G-20 | 20 ug | $314 | |
| L322-30G-50 | 50 ug | $545 | |
| L322-30G-BULK | BULK | Contact Us |
Overview:
LCMT2, also named tRNA wybutosine-synthesizing protein 4 (TYW4), is an S-adenosylmethionine (SAM)-dependent enzyme that involves in the final step of wybutosine biosynthesis pathway (1). Structural study revealed that TYW4 uses one catalytic site for both methylation and methoxycarbonylation process (2).
Gene Aliases:
PPM2; TYW4
Genbank Number:
References:
1. Noma, A., et al. Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA. EMBO J. 25(10):2142-54, 2006.
2. Suzuki, Y., et al. Structural basis of tRNA modification with CO2 fixation and methylation by wybutosine synthesizing enzyme TYW4. Nucleic Acids Res. 37(9):2910-25, 2009.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
90 kDa
There are no related publications available for this product.
Cell Cycle, Metabolic Disorder, Neurobiology
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