Home   >    Proteins   >   COVID-19 Related Products

Anti 2019-nCoV N-Protein hIgG Antibody, HRP conjugated

Recombinant Human Monoclonal IgG Antibody
Catalog No. C19NP-60DH


Shop Online



Catalog No. Pack Size Price (USD)
C19NP-60DH-20 20 ug $205
C19NP-60DH-100 100 ug $405
C19NP-60DH-BULK BULK Contact Us  


Overview:

nCoV N-Protein / Nucleocapsid protein is an RNA-binding protein primarily involved in binding to the viral RNA genome during packaging of viral RNA into a helical ribonucleoprotein or nucleocapsid structure (1). In addition, N-protein regulates viral RNA synthesis during replication/transcription and modulates host-pathogen interactions, such as actin reorganization, host cell cycle progression, and apoptosis (2). N-Protein is abundantly expressed during infection and antibodies against N-Protein have been detected in confirmed cases of Covid-19. Therefore, N-Protein is a potent antigen that provides basis for future vaccine and diagnostic kit development (3).

References:


1. McBride R, et al: The coronavirus nucleocapsid is a multifunctional protein. Viruses. 2014, 6:2991-3018.

2. Surjit M, et al: The nucleocapsid protein of severe acute respiratory syndrome-coronavirus inhibits the activity of cyclin-cyclin-dependent kinase complex and blocks S phase progression in mammalian cells. J Biol Chem. 2006, 281:10669-10681.

3. Zeng W, et al: Biochemical characterization of SARS-CoV-2 nucleocapsid protein. Biochem Biophys Res Commun. 2020, 527(3):618‐623.


Specificity :

Recognizes the 2019-nCoV N-Protein


Cross Reactivity:

SARS-CoV N-Protein


Host Isotype/Clone#:

Human IgG


Stability :

1yr at –20oC from date of shipment


Assay Data :

Binding of Anti-2019-nCoV N-protein, HRP-conjugated (C19NP-60DH) to immobilized 2019-nCoV RBD-N Protein Chimera (C19NSD-G241H) determined by ELISA



Product Datasheets



There are no related publications available for this product.


RELATED PRODUCTS


  Anti 2019-nCoV N-Protein hIgG Antibody , C19NP-60H

  2019-nCoV Nucleocapsid (N) Protein, C19NP-G242H

  2019-nCoV S1 Human IgA ELISA Kit, C19S1-A877

  2019-nCoV S1 Human IgG-IgA-IgM ELISA Kit, C19S1-P877


SIGNALCHEM BIOTECH INC.


About

Terms of Service

Privacy Policy

Get the latest resources, updates and offers in your inbox