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Cas12 (LbCpf1) Protein

Recombinant Lachnospiraceae Cas12(LbCpf1) (1-1227) was expressed in E. coli with a N-terminal GST tag.
Catalog No. C12CR-G241G


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Catalog No. Pack Size Price (USD)
C12CR-G241G-05 5 ug $120
C12CR-G241G-10 10 ug $185
C12CR-G241G-20 20 ug $260
C12CR-G241G-50 50 ug $360
C12CR-G241G-BULK BULK Contact Us  


Overview:

The severe acute respiratory syndrome related novel coronavirus SARS-CoV-2 has caused the pandemic of the respiratory diseases (COVID-19) around the world in 2020 (1). Developing rapid and sensitive diagnostic tools is key for successful patient management and curbing the disease spread. Several CRISPR-Cas12 based SARS-CoV-2 detection assays have been developed (2,3). Comparing to conventional RT-PCR based tests that are hindered by the need for expensive lab instrumentation, Cas12 based tests are ultrasensitive, rapid and in low-cost POCT formats.


Gene Aliases:

Cpf1 (synthetic construct)


Genbank Number:


References:


1. Zhou P, et al: A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020, 579:270-89.

2. Broughton JP, et al: Rapid detection of 2019 novel coronavirus SARS-CoV-2 using a CRISPR-based DETECTR lateral flow assay. medRxiv doi: https://doi.org/10.1101/ 2020.03.06.20032334.

3. Lucia C, et al: An ultrasensitive, rapid, and portable coronavirus SARS-CoV-2 sequence detection method based on CRISPR-Cas12. bioRxiv. doi: https://doi.org/10.1101/ 2020.02.29.971127.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

150 kDa



Product Datasheets



There are no related publications available for this product.


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