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Y-27632 2HCl

ROCK inhibitor
Catalog No. R10-900B


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Catalog No. Pack Size Price (USD)
R10-900B-01 1 mg $88
R10-900B-05 5 mg $209
R10-900B-BULK BULK Contact Us  


Overview:

Specific inhibitor of ROCK family kinases (1). Enhances stem cell survival and proliferation in culture (2). Significantly improves freeze/thaw survival rate for human embryonic stem cells without influencing morphology, karyotype, cell surface markers or differentiation potential (3).

References:


1. T Ishizaki et al. Mol. Pharmacol. 2000 57:976

2. K Gauthaman et al. Stem Cell Rev. 2010 6:86

3. X Li et al. Stem Cells Dev. 2008 17:1079


CAS Registry Number:

129830-38-2


Molecular Formula:

C14H21N3O ∙ 2HCl


Appearance:

White to off-white powder


Melting Point:

N/A


Molecular Weight:

320.3


Purity:

99% (HPLC); NMR (Conforms)


Solubilization:

May be dissolved in DMSO (25 mg/ml)


Aliases:

(R)-(+)-trans-4-(1-Aminoethyl)-N-(-4-pyridyl) cyclohexanecarboxamide dihydrochloride


Storage and Stability:

Storage, Stability and Shipping


Molecular Structure:



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Inflammation, Invasion/Metastasis, Ser/Thr Kinases



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