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DMPQ 2 HCl

PDGFR beta inhibitor
Catalog No. P13-901


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Catalog No. Pack Size Price (USD)
P13-901-05 5 mg $72
P13-901-25 25 mg $270
P13-901-BULK BULK Contact Us  


Overview:

A potent and selective inhibitor of PDGFRβ, IC50=80 nM. Greater than 100-fold more selective compared to EGFR, erB2, p56, PKA and PKC. Cell permeable.

References:


1. RE Dolle et al. J.Med. Chem. 1994 37:2627


CAS Registry Number:

137206-97-4


Molecular Formula:

C16H14N2O2 ∙2HCl


Appearance:

Yellow powder


Melting Point:

231-234oC


Molecular Weight:

339.2


Purity:

>98% (TLC); NMR (Conforms)


Solubilization:

May be dissolved in Water (30 mg/ml) or DMSO (1 mg/ml, warm)


Aliases:

5,7-Dimethoxy-3-(4-pyridinyl) quinoline dihydrochloride


Storage and Stability:

Store desiccated as supplied at room temperature for up to 2 years. Store solutions at -20oC for up to 3 months.


Molecular Structure:



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

AKT/PKB Pathway, Cancer, ERK/MAPK Pathway, Receptor Tyrosine Kinases



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