Home    >   Kinase Inhibitors

WHI-P131

JAK3 inhibitor
Catalog No. J03-901


For enquiry on all Kinase Inhibitors email us at orders@signalchem.com


Catalog No. Pack Size Price (USD)
J03-901-10 10 mg $204
J03-901-50 50 mg $864
J03-901-BULK BULK Contact Us  


Overview:

JAK3 inhibitor. Inhibits human glioblastoma cell adhesion and invasion (1). Increases survival in a mouse ALS model (2). JAK3 inhibitor. Inhibits human glioblastoma cell adhesion and invasion (1). Increases survival in a mouse ALS model (2).

References:


1. RK Narla et al Clin. Cancer Res. 1998 4:2463

2. VN Trieu et al Biochem. Biophys. Res. Commun. 2000 267:22


CAS Registry Number:

202475-60-3


Molecular Formula:

C16H15N3O3 ∙ HCl


Appearance:

Yellow powder


Melting Point:

255-260oC


Molecular Weight:

333.8


Purity:

>98% (TLC); NMR (Conforms)


Solubilization:

May be dissolved in DMSO (50 mg/ml); Ethanol (nil)


Aliases:


1. 4-[(4'-hydroxyphenyl)amino]-6,7-dimethoxyquinazoline, Hydrochloride

2. Janex-1


Storage and Stability:

Store desiccated as supplied at 4oC for up to 2 years. Store solutions at -20oC for up to 2 months.


Molecular Structure:



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Cardiovascular Disease, Cytoplasmic Tyrosine Kinases, Inflammation, JAK/STAT Pathway



SIGNALCHEM BIOTECH INC.


About

Terms of Service

Privacy Policy

Get the latest resources, updates and offers in your inbox