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PX-866

PI3K inhibitor
Catalog No. P27-900


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Catalog No. Pack Size Price (USD)
P27-900-01 1 mg $66
P27-900-05 5 mg $149
P27-900-BULK BULK Contact Us  


Overview:

Inhibits PI3-kinase with selectivity for p110alpha (IC50=0.1 nM). Displays antitumor activity. Irreversible. Cell permeable.

References:


1. NT Ihle et al. Mol. Cancer Ther. 2004 3:763


CAS Registry Number:

502632-66-8


Molecular Formula:

C29H35NO8


Appearance:

Orange powder


Melting Point:

N/A


Molecular Weight:

525.6


Purity:

>98% (TLC); NMR (Conforms)


Solubilization:

May be dissolved in DMSO (25 mg/ml)


Aliases:

(1E,4S,4aR,5R,6aS,9aR)-5-(acetyloxy)-1-[(di-2-propen-1-ylamino) methylene]-4,4a,5,6,6a,8,9,9-a-octahydro-11-hydroxy-4-(methoxymethyl)-4a,6a-dimethyl-cyclopenta [5,6] naphtha [1,2-c] pyran-2,7,10(1H)-trione


Storage and Stability:

Store desiccated as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to 2 months.


Molecular Structure:



Product Datasheets



RESEARCH AREAS

AKT/PKB Pathway, Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Inflammation, Invasion/Metastasis, Lipid Kinases, Metabolic Disorder, Neurobiology, NfkB Pathway, WNT Signaling



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