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PP1

SRC family kinase inhibitor
Catalog No. S19-900


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Catalog No. Pack Size Price (USD)
S19-900-05 5 mg $138
S19-900-25 25 mg $501
S19-900-BULK BULK Contact Us  


Overview:

Potent and selective inhibitor of Src family tyrosine kinases. IC50=5 nM (p65lck), IC50=6 Nm (P59fynT), IC50=170 nM (p60src). Cell permeable.

References:


1. JH Hanke et al J. Biol. Chem 1996 271:695


CAS Registry Number:

172889-26-8


Molecular Formula:

C16H19N5


Appearance:

White to off white powder


Melting Point:

N/A


Molecular Weight:

281.4


Purity:

98% (TLC); NMR (Conforms)


Solubilization:

May be dissolved in DMSO (25 mg/ml); Ethanol (10 mg/ml)


Aliases:

4-Amino-1-tert-butyl-3-(4-methylphenyl) pyrazolo [3,4-d] pyrimidine


Storage and Stability:

Store as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to 2 months.


Molecular Structure:



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Angiogenesis, Apoptosis/Autophagy, Cancer, Cytoplasmic Tyrosine Kinases, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, JAK/STAT Pathway


RELATED PRODUCTS


  PP1/PP2A Substrate, P50-58

  PP2B Substrate, P51-58


SIGNALCHEM BIOTECH INC.


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