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AS-041164

PI3K gamma inhibitor
Catalog No. P29-901


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Catalog No. Pack Size Price (USD)
P29-901-10 10 mg $94
P29-901-50 50 mg $369
P29-901-BULK BULK Contact Us  


Overview:

A selective PI 3-Kgamma isoform inhibitor (IC50 = 0.24, 1.45, 0.07 and 1.70 uM for alpha, beta, gamma and delta isoforms respectively). Blocks neutrophil recruitment and displays anti-inflammatory activity (1). Active in vivo.

References:


1. C Ferrandi et al. J. Pharmacol. Exp. Ther. 2007 322:923


CAS Registry Number:

6318-41-8


Molecular Formula:

C11H7NO4S


Appearance:

Yellow Solid


Melting Point:

N/A


Molecular Weight:

249.2


Purity:

>98% (TLC); NMR (Conforms)


Solubilization:

May be dissolved in DMSO (25 mg/mL)


Aliases:


1. 5-Benzo[1,3]dioxol-5-ylmethylene-thiazolidine-2,4-dione

2. NSC31098


Storage and Stability:

Store desiccated as supplied at ambient temperature for up to 1 year. Store solutions at -20oC for 1 month.


Molecular Structure:



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

AKT/PKB Pathway, Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Inflammation, Invasion/Metastasis, Lipid Kinases, Metabolic Disorder, Neurobiology, NfkB Pathway, WNT Signaling



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