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JNK Inhibitor IX

JNK inhibitor
Catalog No. M34-901


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Catalog No. Pack Size Price (USD)
M34-901-10 10 mg $83
M34-901-50 50 mg $325
M34-901-BULK BULK Contact Us  


Overview:

Inhibits JNK2 and JNK3 via binding to the ATP binding domain. Displays little or no activity against JNK1, p38 and a panel of 30 other kinases1.

References:


1. RM Angell et al. Bioorg. Med. Chem. Lett. 2007 17:1296


CAS Registry Number:

312917-14-9


Molecular Formula:

C20H16N2OS


Appearance:

Off-White powder


Molecular Weight:

332.4


Purity:

>98% (TLC); NMR (Conforms)


Solubilization:

May be dissolved in DMSO (13mg/ml); or ethanol (4 mg /ml, warm)


Aliases:

N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-1-naphthalenecarboxamide


Storage and Stability:

Store desiccated as supplied at ambient temperature for up to 2 years. Store solutions at -20oC for up to 3 months.


Molecular Structure:



Product Datasheets



RESEARCH AREAS

Apoptosis/Autophagy, Cardiovascular Disease, Cellular Stress, Inflammation, JNK/SAPK Pathway, Neurobiology, NfkB Pathway, Ser/Thr Kinases


RELATED PRODUCTS


  JNK1, Active, M33-10G

  JNK2, Active, M34-10BG

  MEK4 (MAP2K4), Active, M05-10G

  MEK7, Active, M08-10G


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