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HA-100 2HCl

Pan-kinase inhibitor
Catalog No. K10-900F


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Catalog No. Pack Size Price (USD)
K10-900F-05 5 mg $83
K10-900F-25 25 mg $303
K10-900F-BULK BULK Contact Us  


Overview:

Inhibits the following kinases PKG (IC50=4 µM), PKA (IC50=8 µM), PKC (IC50=12 µM)1. Increases human fibroblast reprogramming efficiency with PD0325901, CHIR99021, A83-01 and hLIF2. Improves single cell survival and supports high cloning efficiency in human pluripotent stem cells3.

References:


1. M Hagiwara et al. Mol. Pharmacol. 1987 32:7

2. J Yu et al. PLoS One 2011 6(3):e17557

3. G Chen et al. Nature Methods 2011 8:424


CAS Registry Number:

84468-24-6


Molecular Formula:

C13H15N3O2S • 2HCl


Appearance:

White to off white powder


Molecular Weight:

350.3


Purity:

>98% (HPLC); NMR (conforms)


Solubilization:

May be dissolved in DMSO (30 mg/ml); or water (40 mg/ml)


Aliases:

5-(1-Piperazinylsulfonyl)isoquinoline dihydrochloride


Storage and Stability:

Store desiccated as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to two months.


Molecular Structure:



Product Datasheets



There are no related publications available for this product.


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