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SR-3576

JNK3 inhibitor
Catalog No. M35-901


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Catalog No. Pack Size Price (USD)
M35-901-05 5 mg $83
M35-901-25 25 mg $303
M35-901-BULK BULK Contact Us  


Overview:

Potent and selective JNK3 inhibitor. IC50= 7 nM and >2800-fold selective over p381. Cell permeable.

References:


1. T Kamenecka et. al J. Biol. Chem. 2009 284:12853


CAS Registry Number:

1164153-22-3


Molecular Formula:

C27H27N5O5


Appearance:

Off White powder


Molecular Weight:

501.53


Purity:

>98% (TLC); NMR (Conforms)


Solubilization:

May be dissolved in DMSO (30 mg/ml) or ethanol (10 mg/ml, warm)


Aliases:

3-(5-(3-m-Tolylureido)-1H-indazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide


Storage and Stability:

Store desiccated as supplied at -20oC temperature for up to 2 years. Store solutions at -20oC for up to 1 month.


Molecular Structure:



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Apoptosis/Autophagy, Cardiovascular Disease, Cell Cycle, Inflammation, JNK/SAPK Pathway, Neurobiology, NfkB Pathway, Ser/Thr Kinases



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