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IQ-1S

JNK3 inhibitor
Catalog No. M35-901B


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Catalog No. Pack Size Price (USD)
M35-901B-05 5 mg $83
M35-901B-25 25 mg $303
M35-901B-BULK BULK Contact Us  


Overview:

JNK3 inhibitor (Kd = 87, 360 and 390 nM for JNK3, JNK2 and JNK1, respectively). Displays anti-inflammatory and immunosuppresive activity. Inhibits LPS-induced proinflammatory cytokine and nitric oxide release in vitro1.

References:


1. IA Schepetkin et al. Mol. Pharmacol. 2012 81:832

2. IA Schepetkin et al. J. Pharmacol. Exp. Ther. 2015 353:505


CAS Registry Number:

1421610-21-0


Molecular Formula:

269.2


Appearance:

Yellow powder


Molecular Weight:

269.2


Purity:

>98% (TLC); NMR (Conforms)


Solubilization:

May be dissolved in DMSO (15 mg/ml)


Aliases:

11H-Indeno[1,2-b]quinoxalin-11-one oxime, sodium salt


Storage and Stability:

Store desiccated as supplied at -20oC temperature for up to 2 years. Store solutions at -20oC for up to 1 month.


Molecular Structure:



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Apoptosis/Autophagy, Cardiovascular Disease, Cellular Stress, Inflammation, JNK/SAPK Pathway, Neurobiology, NfkB Pathway, Ser/Thr Kinases


RELATED PRODUCTS


  JNK3, Active, M35-10BG


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