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Amlexanox

TBK1 Inhibitor
Catalog No. T02-901


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Catalog No. Pack Size Price (USD)
T02-901-100 100 mg $325
T02-901-500 500 mg $765
T02-901-BULK BULK Contact Us  


Overview:

Inhibits TANK-binding kinase 1 (TBK1) and IKKε (IC50=1.2 µM)2. Clinically useful in the treatment of aphthus ulcers.

References:


1. L Koch Nat. Rev. Endocrinol. 2013 9:185

2. SM Reilly et al. Nat. Med. 2012 19:313


CAS Registry Number:

68302-57-8


Molecular Formula:

C16H14N2O4


Appearance:

White crystalline powder


Molecular Weight:

298.3


Purity:

>98% (TLC); NMR (Conforms)


Solubilization:

May be dissolved in DMSO (60 mg/ml). Insoluble in ethanol


Aliases:

2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid


Storage and Stability:

Store desiccated as supplied at RT for up to 2 years. Store solutions at -20oC for up 3 months.


Molecular Structure:



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Inflammation, NfkB Pathway, Ser/Thr Kinases


RELATED PRODUCTS


  TBK1, Active, T02-10G


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