Full-length recombinant human PCTK3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. P11-34G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| P11-34G-20 | 20 ug | $215 | |
| P11-34G-50 | 50 ug | $435 | |
| P11-34G-BULK | BULK | Contact Us |
Overview:
PCTK3 or PCTAIRE protein kinase 3 is a member of the cdc2/cdkx subfamily of the ser/thr family of protein kinases. PCTK3 is thought to play a role in terminally differentiated neurons and it contains an N-terminal extension relative to CDC2 (1). PCTK3 is expressed in a variety of human cell lines and tissues (2). Elevation in the protein levels of PCTAIRE 3 in the temporal cortex of Alzheimer's disease relative to control brains, have been observed. It is proposed that PCTAIRE 3 is a paired helical filaments-associated kinase that modulates tau phosphorylation.
Gene Aliases:
PCTAIRE, PCTAIRE3
Genbank Number:
References:
1. Meyerson, M.et.al: A family of human cdc2-related protein kinases. EMBO J. 11: 2909-2917, 1992.
2. Okuda, T.et.al: PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family. Oncogene 7: 2249-2258, 1992.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~76 kDa
There are no related publications available for this product.
Cancer, Cell Cycle, Ser/Thr Kinases
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