Recombinant Human Eotaxin (CCL11) was expressed in E. coli cells.
Catalog No. E852-40N
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| E852-40N-20 | 20 ug | $160 | |
| E852-40N-1000 | 1 mg | $3650 | |
| E852-40N-BULK | BULK | Contact Us |
Overview:
Eotaxin belongs to the platelet factor-4 family of chemokines. The gene symbol is SCYA11. The factor is being referred to also as Eotaxin-1 and has been renamed CCL11. Eotaxin induces substantial accumulation of eosinophils in the skin without significantly affecting the accumulation of neutrophils. Eotaxin is a potent stimulator of both guinea pig and human eosinophils in vitro. The Eotaxin receptor is a G-protein-coupled receptor selectively expressed in human eosinophils.
Gene Aliases:
SCYA11, C-C motif chemokine 11, Eosinophil chemotactic protein, Small-inducible cytokine A11.
Genbank Number:
Storage, Stability and Shipping:
Upon reconstitution, this cytokine can be stored in working aliquots at 2o - 8oC for one month, or at -20oC for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Endotoxin Level:
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Molecular Weight:
8.5 kDa
Reconstitution Protocol:
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Sample Cell Assay Data:
Activity was determined by the ability to induce chemotaxis of purified eosinophils at concentrations ranging between 50-100 ng/mL.
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Purity:
Recombinant Human Eotaxin (CCL11) resolved on a 17% SDS-PAGE gel under reducing conditions and stained with Coomassie Brilliant Blue G-250.
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There are no related publications available for this product.
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