Recombinant Human CCL22 was expressed in E. coli cells.
Catalog No. M832-40N
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| M832-40N-20 | 20 ug | $355 | |
| M832-40N-BULK | BULK | Contact Us |
Overview:
CCL22 (monocyte-derived chemokine) was described initially as a constitutively produced, thymus-specific chemokine, implicated in the recruitment of T cells . One of the functions of CCL22 originally described was induction of migration of CCR4+ Th2 cells, but it has additionally been shown to regulate migration of Tregs. CCL22 has been implicated in a number of diseases, including allergen-induced lung inflammation, atopic dermatitis, and lymphoma. Similarly, a presumed role for CCR4+ cells has been suggested for endotoxic shock, rheumatoid arthritis, T cell lymphoma, and autoimmune diabetes.
Gene Aliases:
STCP-1, ABCD-1, CCL22, CC chemokine STCP-1, MDC(1-69), SCYA22, Small-inducible cytokine A22, Stimulated T-cell chemotactic protein 1, MDC, C-C motif chemokine 22, Recombinant Human Macrophage-Derived Chemokine (CCL22).
Genbank Number:
Storage, Stability and Shipping:
Upon reconstitution, this cytokine can be stored in working aliquots at 2o - 8oC for one month, or at -20oC for six months. Avoid repeated freeze/thaw cycles.
Endotoxin Level:
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Molecular Weight:
8.0 kDa
Reconstitution Protocol:
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Sample Cell Assay Data:
Determined by its ability to chemoattract human T cells using a concentration range of 10-50 ng/mL.
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Purity:
Recombinant Human CCL22 resolved on a 17% SDS-PAGE gel under reducing conditions and stained with Coomassie Brilliant Blue G-250.
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There are no related publications available for this product.
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