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p38 beta, Unactive

Recombinant full-length human p38beta was expressed in E. coli cells using an N-terminal GST tag.
Catalog No. M36-14G


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Catalog No. Pack Size Price (USD)
M36-14G-20 20 ug $215
M36-14G-50 50 ug $435
M36-14G-BULK BULK Contact Us  


Overview:

p38-β is a member of the p38 MAP kinase family and is activated by both proinflammatory cytokines and environmental stress (1). The p38-beta is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase (2). Alternatively spliced transcript variants encoding the same protein have been observed.


Gene Aliases:

MAPK11; SAPK2; p38-2; PRKM11; SAPK2B; p38b; P38b2


Genbank Number:


References:


1. Jiang, Y. et al: Characterization of the structure and function of a new mitogen-activated protein kinase (p38-beta). J. Biol. Chem. 271: 17920-17926, 1996.

2. Stein, B. et al: p38-2, a novel mitogen-activated protein kinase with distinct properties. J. Biol. Chem. 272: 19509-19517, 1997.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles


Molecular Weight:

~69 kDa



Product Datasheets



RESEARCH AREAS

Angiogenesis, Apoptosis/Autophagy, Cardiovascular Disease, Cellular Stress, Inflammation, Metabolic Disorder, Neurobiology, NfkB Pathway, p38 Pathway, Ser/Thr Kinases


RELATED PRODUCTS


  p38 alpha, Unactive, M39-14G

  p38 gamma, Unactive, M37-14G

  p38 alpha, Active, M39-10BG

  p38 beta, Active, M36-10BG


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