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UBE2L3 (UBCH7) Protein

Recombinant full-length human UBE2L3 was expressed in E. coli cells using an N-terminal His tag.
Catalog No. U228-30H


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Catalog No. Pack Size Price (USD)
U228-30H-20 20 ug $105
U228-30H-50 50 ug $160
U228-30H-BULK BULK Contact Us  


Overview:

Ubiquitin-conjugating enzyme E2 L3 (UBE2L3) belongs to the ubiquitin-conjugating enzyme family of the ubiquitin-proteasome pathway, facilitating the transfer of activated ubiquitin from ubiquitin-activating enzyme to target proteins with the help of ubiquitin-protein ligases. It specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases and does not function with most RING-containing E3 ubiquitin-protein ligases. Catalyzes 'Lys-11'-linked polyubiquitination in vitro.


Gene Aliases:

E2-F1; L-UBC; UBCH7; UbcM4


Genbank Number:


References:


1. Nuber U, et al: Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5. J Biol Chem. 1996 271:2795-800

2. David Y, et al: The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines. J Biol Chem. 2010 19;285:8595-604.

3. http://www.uniprot.org/uniprot/P68036


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

18 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Cell Cycle, Neurobiology


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