AMPK Activator
Catalog No. P47-900B
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| P47-900B-50 | 50 mg | $75 | |
| P47-900B-250 | 250 mg | $270 | |
| P47-900B-BULK | BULK | Contact Us |
Overview:
Activates AMP-activated protein kinase (AMPK). Promotes ligand-independent activation of the insulin receptor (1). Promotes skeletal muscle autophagy via activation of FoxO3a (2). Controls smooth muscle cell hyperproliferation in vascular disease (3). Cell permeable.
References:
1. Chopra et al. Diabetologia 2012 55:783
2. AM Sanchez et al. J. Cell Biochem. 2012 113:695
3. N Ferri et al. Vascul. Pharmacol. 2012 56:9
CAS Registry Number:
2627-69-2
Molecular Formula:
C9H14N4O5
Appearance:
Off white solid
Melting Point:
213-214oC
Molecular Weight:
258.2
Purity:
>99% (TLC); NMR (Conforms)
Solubilization:
Soluble in DMSO (15 mg/ml); or water (15 mg/ml)
Aliases:
1. 5-Aminoimidazole-4-carboxamide 1-B-D-ribofuranoside
2. Acadesine
Storage and Stability:
Store desiccated as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to 3 months.
Molecular Structure:
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There are no related publications available for this product.
Apoptosis/Autophagy, Cancer, Cellular Stress, Metabolic Disorder, Ser/Thr Kinases
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