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MINDY4 Protein

Recombinant full-length human MINDY4 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. M534-30G


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Catalog No. Pack Size Price (USD)
M534-30G-20 20 ug $215
M534-30G-50 50 ug $435
M534-30G-BULK BULK Contact Us  


Overview:

MINDY 4 is a member of motif interacting with Ub-containing novel DUB family. It is found in all eukaryotes and selectively cleaves K48-linked polyUb, a signal that targets protein degradations (1). It has been associated with teratospermina and solid tumors including colon cancer (2,3). The expression and function of MINDY4 has yet to be characterized, however it has been shown to play a role in sustaining cell survival in vitro and regulating growth in vivo. (3)


Gene Aliases:

FAM188B, C7orf67


Genbank Number:


References:


1. Abdul Rehman SA, et al: (2016) MINDY-1 is a Member of an evolutionarily conserved and structurally distinct new family of deubiquitinating enzymes. Mol Cell. 63(1):146‐155.

2. GEO Profiles: GDS2697 record.

3. Choi ES, et al: (2018) FAM188B enhances cell survival via interaction with USP7. Cell Death Dis. 9(6):633.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

120 kDa



Product Datasheets



Safety Datasheet



There are no related publications available for this product.


RESEARCH AREAS

Cancer



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