Recombinant SENP2 (360-end) was expressed in E. coli cells using an N-terminal His tag.
Catalog No. S532-381H
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
S532-381H-05 | 5 ug | $226 | |
S532-381H-10 | 10 ug | $325 | |
S532-381H-BULK | BULK | Contact Us |
Overview:
Sentrin-specific protease 2 (SENP2) is a protease that catalyzes the hydrolysis of an alpha-linked peptide bond of the small ubiquitin-like modifier (SUMO) propeptides leading to the mature form of the proteins and the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted protein. SENP2 plays a role in the formation of adipocytes by desumolyating and promoting CEPBP stabilization (1). SENP2 also binds to Nup153, a nucleoporin that is confined to the nucleoplasmic face of the pore and localization of SENP2 to the pore may spatially restrict the activity of this enzyme (2).
Gene Aliases:
KIAA1331, SMT3IP2, AXAM2
Genbank Number:
References:
1. Chung, S.S. et al: Control of adipogenesis by the SUMO-specific protease SENP2. Mol. Cell. Biol. 30:2135-2146, 2010.
2. Hang, J. & Dasso, M: Association of the human SUMO-1 protease SENP2 with the nuclear pore. J. Biol. Chem. 277 (22): 19961–6, 2002.
Specific Activity:
Sample Activity Plot. For specific information on a given lot, see related technical data sheet.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
28 kDa
There are no related publications available for this product.
Cancer, Cardiovascular Disease, Cell Cycle, Cellular Stress, Invasion/Metastasis, Metabolic Disorder
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