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PLCB1 Protein

Recombinant full-length human PLCB1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. P441-30G


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Catalog No. Pack Size Price (USD)
P441-30G-20 20 ug $314
P441-30G-50 50 ug $545
P441-30G-BULK BULK Contact Us  


Overview:

1-phosphatidylinositol 4, 5-bisphosphate phosphodiester-ase beta-1 (PLCB1) is one of the best characterized isoenzymes in the inositide specific phospholipase C (PI-PLC) family. Responsible for the hydrolysis of the phosphatidilinool-4, 5-bisphophate (PIP2), generating the second messengers inositol-1, 4, 5-triphosphate and di-acylglycerol. It is a key molecule for nuclear inositide signaling, where it plays a role in cell cycle progression, proliferation and differentiation.


Gene Aliases:

EIEE12; PI-PLC; PLC-154; PLC-I; PLC154; PLCB1A; PLCB1B


Genbank Number:


References:


1. Faenza I, et al: A role for PLCbeta1 in myotonic dystrophies type 1 and 2. Faseb J. 26:3042–3048, 2012.

2. Faenza I, et al: Nuclear inositide specific phospholipase C signalling - interactions and activity. FEBS J. 280(24):6311-21, 2013.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

180 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Cardiovascular Disease, Cellular Stress, Metabolic Disorder, Neurobiology


RELATED PRODUCTS


  PLCD4 Protein, P442-30DG


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