Home    >   Isoform Specific Antibodies

Anti-p38 beta

Rabbit Polyclonal Antibody
Catalog No. M36-63R


For enquiry on all Isoform Specific Antibodies email us at orders@signalchem.com


Catalog No. Pack Size Price (USD)
M36-63R-25 25 ug $127
M36-63R-100 100 ug $347
M36-63R-BULK BULK Contact Us  


Overview:

p38β is a member of the p38 MAP kinase family and is activated by both proinflammatory cytokines and environmental stress (1). The p38β is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase (2). Alternatively spliced transcript variants encoding the same protein have been observed.

References:

1. Jiang, Y. et al: Characterization of the structure and function of a new mitogen-activated protein kinase (p38-beta). J. Biol. Chem. 271: 17920-17926, 1996.

2. Stein, B. et al: p38-2, a novel mitogen-activated protein kinase with distinct properties. J. Biol. Chem. 272: 19509-19517, 1997.


Specificity:

Recognizes the p38β protein


Cross Reactivity:

Western blot human p38b

p38b from other species may also be detectable.


Host:

Rabbit


Immunogen:

C-terminal peptide of p38β conjugated to ovalbumin


Purification:

Affinity chromatography


Stability:

Store at 4°C (add 0.1% NaN3) for several months, and at -20°C for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For optimal performance, avoid repeated handling and multiple freeze/thaw cycles.


Sample Western Blot:

Representative western blot (1:1000) using 20ng of p38α, p38β, p38γ, and p38δ recombinant protein.



Product Datasheets



RESEARCH AREAS

Angiogenesis, Apoptosis/Autophagy, Cardiovascular Disease, Cellular Stress, Inflammation, Metabolic Disorder, Neurobiology, NfkB Pathway, p38 Pathway


RELATED PRODUCTS


  p38 beta, Unactive, M36-14G

  Anti-Rabbit HRP, G33-62G

  p38 gamma, Active, M37-10BG

  p38 delta, Active, M38-10BG


SIGNALCHEM BIOTECH INC.


About

Terms of Service

Privacy Policy

Get the latest resources, updates and offers in your inbox