Enzymes, Signaling Proteins, Extracellular Ligands, Signaling Reagents, Antibodies

Catalog No.	Pack Size	Price (USD)
P282-63R-100	100 ug	$595
P282-63R-BULK	BULK	Contact Us

Catalog No.

Pack Size

Price (USD)

P282-63R-100

100 ug

$595

P282-63R-BULK

BULK

References:

1. Liu B et al: Inhibition of Stat1-mediated gene activation by PIAS1. Proc. Natl. Acad. Sci. USA1998; 95: 10626-31.

2. Shuai K et al: Regulation of gene-activation pathways by PIAS proteins in the immune system. Nat. Rev. Immunol.2005; 5:593-605.

3. Chung CD et al: Specific inhibition of Stat3 signal transduction by PIAS3. Science1997; 278:1803-5.

4. Wang L B et al: Differential PIAS3 expression in human malignancy. Oncol. Rep.2004; 11:1319-24.

5. Zhang Q et al: Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma. J. Immunol.2002; 168:466-7.

Specificity:

Recognizes the PIAS3 protein

Cross Reactivity:

Human, Mouse and Rat

Host / Isotype / Clone#:

Rabbit, IgG

Immunogen:

PIAS3 antibody was raised against a 12 amino acid synthetic peptide near the carboxy terminus of human PIAS3

Purification:

Affinity chromatography

Stability:

Store at 4^oC (add 0.1% NaN₃) for several months, and at -20^oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Sample Data:

Western blot analysis of PIAS3 in K562 cell lysate with PIAS3 antibody at 1 ug/mL.