Enzymes, Signaling Proteins, Extracellular Ligands, Signaling Reagents, Antibodies

Catalog No.	Pack Size	Price (USD)
E96-363R-100	100 ug	$595
E96-363R-BULK	BULK	Contact Us

Catalog No.

Pack Size

Price (USD)

E96-363R-100

100 ug

$595

E96-363R-BULK

BULK

References:

1. Chen H et al: Cloning of a human homolog of the Drosophila enhancer of zeste gene (EZH2) that maps to chromosome 21q22.2. Genomics 1996; 38:30-7

2. Margueron R et al: Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms. Mol. Cell 2008; 32:503-18.

3. Shen X et al: EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency. Mol. Cell 2008; 32:491-502.

4. Ezhkova E et al: EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair. Genes Dev. 2011; 25:485-98.

Specificity:

Recognizes the EZH2 protein and is predicted to not cross-react with EZH1

Cross Reactivity:

Human, Mouse and Rat

Host / Isotype / Clone#:

Rabbit, IgG

Immunogen:

EZH2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human EZH2.

Purification:

Affinity chromatography

Stability:

Store at 4^oC (add 0.1% NaN₃) for several months, and at -20^oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Sample Data:

Western blot analysis of EZH2 in 293 cell lysate with EZH2 antibody at 1 ug/mL.