Enzymes, Signaling Proteins, Extracellular Ligands, Signaling Reagents, Antibodies

Catalog No.	Pack Size	Price (USD)
D09-63R-100	100 ug	$595
D09-63R-BULK	BULK	Contact Us

Catalog No.

Pack Size

Price (USD)

D09-63R-100

100 ug

$595

D09-63R-BULK

BULK

References:

1. Park J et al: Two key genes closely implicated with the neuropathological characteristics in Down Syndrome: DYRK1A and RCAN1. BMB Reports 2009; 42:6-15.

2. Park J et al: Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells. J. Biol. Chem. 2010; 285:31895-906

3. Li D et al: Direct association of Sprouty-related protein with and EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions. J. Biol. Chem. 2010; 285:35374-85.

Specificity:

Recognizes the DYRK1A protein

Cross Reactivity:

Human and Mouse

Host / Isotype / Clone#:

Rabbit, IgG

Immunogen:

DYRK1A antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human DYRK1A.

Purification:

Affinity chromatography

Stability:

Store at 4^oC (add 0.1% NaN₃) for several months, and at -20^oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Sample Data:

Western blot analysis of DYRK1A in HeLa cell lysate with DYRK1A antibody at (A) 1 and (B) 2 ug/mL.