Enzymes, Signaling Proteins, Extracellular Ligands, Signaling Reagents, Antibodies
| Shopping Cart EN/中文
Due to Good Friday holiday, all delivery service requests will not be processed on April 19, 2019. Regular delivery schedule will resume on April 22, 2019.


Product Name Catalog Number Pack Size Price(USD)  
Anti-AKT3 A18-63R-25 25 ug $127 Contact Us
Anti-AKT3 A18-63R-100 100 ug $347 Contact Us
Anti-AKT3 A18-63R-BULK BULK Contact Us  

Description: Rabbit Polyclonal Antibody

Specificity : Recognizes the AKT3 protein

Cited Applications : WB

Cross Reactivity : Western blot AKT3 from human and mouse cells

AKT3 from other species may also be detectable.

Host : Rabbit

Immunogen : Protein Code: Q9Y243

Purification : Affinity Chromatography

Stability : Store at 4oC (add 0.1% NaN3) for several months, and at -20oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For optimal performance, avoid repeated handling and multiple freeze/thaw cycles.

Sample Data : Representative western blot (1:1000) with Anti-AKT3 using 20 ng of human full length recombinant AKT1, AKT2, and AKT3.

Scientific Background : AKT 3 or Protein Kinase B (PKB ) is a serine/threonine kinase that is a member of the AKTγ (PKBγB family. AKT 3 is activated in cells exposed to diverse stimuli such as hormones, growth factors, and extracellular matrix components (1). AKT 3 phosphorylates and regulates the function of many cellular proteins involved in processes that include cellular metabolism, survival/apoptosis, and proliferation. Recent evidence indicates that AKT 3 is frequently overexpressed in many types of human cancers including breast and prostate (2).

References :
1. Coffer, PJ. et al: Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem J. 1998 Oct 1; 335 (Pt 1): 1-13.

2. Anderson, KE. et al: Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B. Curr Biol. 1998 Jun 4;8(12): 684-91.

Product Sheets

Research Areas
Cancer, Cell Cycle, Inflammation, Neurobiology,

Related Products
publication book Product Related Publications

  Terms of Service | Privacy Policy  
  @ 2018 SignalChem.All rights reserved