Home   >   Enzymes   >   Kinases

PAK7, Active

Recombinant full-length human PAK7 was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
Catalog No. P07-10G


Shop Online



Catalog No. Pack Size Price (USD)
P07-10G-05 5 ug $226
P07-10G-10 10 ug $325
P07-10G-BULK BULK Contact Us  


Overview:

PAK7 (also known as PAK5) is a novel human PAK family kinase that contains a CDC42/Rac1 interactive binding (CRIB) motif at the N-terminus and a Ste20-like kinase domain at the C-terminus (1). The p21-activated kinase (PAK) family of protein kinases has recently attracted considerable attention as an effector of Rho family of small G proteins and as an upstream regulator of MAPK signalling pathways during cellular events such as re-arrangement of the cytoskeleton and apoptosis. PAK7 like the other Paks has been implicated in the regulation of cell morphology, motility and transformation.


Gene Alisases:

PAK5; KIAA1264; MGC26232


Genbank Number:


References:


1. Pandey, A. et al: Cloning and characterization of PAK5, a novel member of mammalian p21-activated kinase-II subfamily that is predominantly expressed in brain. Oncogene. 2002 May 30;21(24):3939-48.


Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~130 kDa



There are no related publications available for this product.


RESEARCH AREAS

Cancer, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Neurobiology, Ser/Thr Kinases


RELATED PRODUCTS


  AKT (PKB) Substrate, A05-58

  PAK3, Active, P04-10G

  Anti-PAK1, P02-63R

  PAK6, Active, P06-10G


SIGNALCHEM BIOTECH INC.


About

Terms of Service

Privacy Policy

Get the latest resources, updates and offers in your inbox