UBA6 or ubiquitin-like modifier activating enzyme 6 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (1). UBA6 is highly expressed in human tissues and cell lines. E1-L2 activates both ubiquitin and FAT10 (2).
E1-L2, MOP-4, UBE1L2, DKFZp451P021
1. Jin, J. et.al: Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging. Nature 447: 1135-1138, 2007.
2. Chiu, Y. H. et.al: E1-L2 activates both ubiquitin and FAT10. Molec. Cell 27: 1014-1023, 2007.
Sample Activity Plot. For specific information on a given lot, see related technical data sheet.
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
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