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GROWTH FACTORS - Eotaxin (CCL11) (E852-40N)

Product Name Catalog Number Pack Size Price(USD)  
Eotaxin (CCL11) E852-40N-20 20 ug $160 Contact Us
Eotaxin (CCL11) E852-40N-1000 1 mg $3152 Contact Us
Eotaxin (CCL11) E852-40N-BULK BULK Contact Us  

Description: Recombinant Human Eotaxin (CCL11) was expressed in E. coli cells.

Storage, Stability and Shipping : Upon reconstitution, this cytokine can be stored in working aliquots at 2o - 8oC for one month, or at -20oC for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Applications : Cell Assay

Endotoxin Level : <1.0 EU/μg of recombinant protein as determined by the LAL method.

Molecular Weight : 8.5 kDa

Gene Aliases : SCYA11, C-C motif chemokine 11, Eosinophil chemotactic protein, Small-inducible cytokine A11.

Reconstitution Protocol : A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Scientific Background : Eotaxin belongs to the platelet factor-4 family of chemokines. The gene symbol is SCYA11. The factor is being referred to also as Eotaxin-1 and has been renamed CCL11. Eotaxin induces substantial accumulation of eosinophils in the skin without significantly affecting the accumulation of neutrophils. Eotaxin is a potent stimulator of both guinea pig and human eosinophils in vitro. The Eotaxin receptor is a G-protein-coupled receptor selectively expressed in human eosinophils.

Sample Cell Assay Data : Activity was determined by the ability to induce chemotaxis of purified eosinophils at concentrations ranging between 50-100 ng/mL.

Purity : Recombinant Human Eotaxin (CCL11) resolved on a 17% SDS-PAGE gel under reducing conditions and stained with Coomassie Brilliant Blue G-250.

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