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GROWTH FACTORS - CCL21 (E882-40N)

Product Name Catalog Number Pack Size Price(USD)  
CCL21 E882-40N-20 20 ug $248 Contact Us
CCL21 E882-40N-100 100 ug $413 Contact Us
CCL21 E882-40N-1000 1 mg $3163 Contact Us
CCL21 E882-40N-BULK BULK Contact Us  


Description: Recombinant Human CCL21 was expressed in E. coli cells.


Storage, Stability and Shipping : The lyophilized protein is stable for at least one year from date of receipt at -70oC. Upon reconstitution, this cytokine can be stored in working aliquots at 2o - 8oC for one month, or at -20oC for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Applications : Cell Assay

Endotoxin Level : <1.0 EU/μg of recombinant protein as determined by the LAL method.

Molecular Weight : 12.0 kDa

Gene Aliases : C-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, SLC, Small-inducible cytokine A21, SCYA21, Recombinant Human Secondary Lymphoid-Tissue Chemokine (CCL21).

Reconstitution Protocol : A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Scientific Background : CCL21, which is a member of the family of CC-Chemokines, has a unique 36 (murine) or 37 (human) amino acid carboxyl-terminal extension not seen in other chemokines. CCL21 selectively stimulates the chemotaxis of adult T lymphocytes and is expressed preferentially in lymph node tissue. CCL21 is critical for adult T cell adhesion to high endothelial venules in lymph nodes, a rate-limiting step for T cell trafficking through nodal tissue.

Sample Cell Assay Data : Determined by its ability to chemoattract total lymphocyte population using a concentration range of 10-100 ng/mL.



Purity : Recombinant Human CCL21 resolved on a 17% SDS-PAGE gel under reducing conditions and stained with Coomassie Brilliant Blue G-250



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Research Areas
Cancer,

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