Enzymes, Signaling Proteins, Extracellular Ligands, Signaling Reagents, Antibodies
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Product Name Catalog Number Pack Size Price(USD)  
AITRL (TNFSF18) A828-40N-30 30 ug $160 Contact Us
AITRL (TNFSF18) A828-40N-200 200 ug $688 Contact Us
AITRL (TNFSF18) A828-40N-1000 1 mg $3163 Contact Us
AITRL (TNFSF18) A828-40N-BULK BULK Contact Us  

Description: Recombinant Human AITRL (TNFSF18) was expressed in E. coli cells.

Storage, Stability and Shipping : The lyophilized protein is stable for at least one year from date of receipt at -70oC. Upon reconstitution, this cytokine can be stored in working aliquots at 2o - 8oC for one month, or at -20oC for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Applications : Cell Assay

Endotoxin Level : <1.0 EU/μg of recombinant protein as determined by the LAL method.

Molecular Weight : 14.2 kDa

Gene Aliases : Activation-inducible TNF-related ligand, AITRL, Glucocorticoid-induced TNF-related ligand, GITRL, hGITRL, Tumor necrosis factor ligand superfamily member 18, TNFSF18, TL-6, Recombinant Human Activation-Induced TNFR Member Ligand (TNFSF18).

Reconstitution Protocol : Reconstitute at 0.1 mg/mL in PBS containing at least 0.1% human or bovine serum albumin.

Scientific Background : TNFSF18 is a transmembrane glycoprotein which is expressed in vascular endothelial cells as well as neurons, antigen presenting cells, CD4­- CD8- double negative thymic precursors, and in the eye. TNFSF18 works to mediate the interactions between T cells and endothelial cells, and T cell growth. It has been shown that TNFSF18's expression is transiently up-regulated by proinflammatory stimulation.

Sample Cell Assay Data :

Purity : Recombinant Human AITRL (TNFSF18) resolved on a 17% SDS-PAGE gel under reducing conditions and stained with Coomassie Brilliant Blue G-250.

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