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CAMK2 beta, Active

Recombinant full-length human CAMK2beta was expressed by baculovirus in Sf9 cells using an N-terminal His tag.
Catalog No. C12-10H


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Catalog No. Pack Size Price (USD)
C12-10H-05 5 ug $226
C12-10H-10 10 ug $325
C12-10H-BULK BULK Contact Us  


Overview:

CAMK2β belongs to the serine/threonine protein kinase family and to the type II multifunctional Ca(2+)/calmodulin-dependent protein kinase subfamily. CAMK2β showed wide tissue and cell distribution, and one of CAMK2β variant predominated in adult brain (1). The ratio of CAMK2α and CAMK2β protein levels were inversely related during activity in hippocampal neurons (2). CAMK2β is a prominent kinase in the central nervous system and may function in long-term potentiation and neurotransmitter release.


Gene Alisases:

CAMKB, CAM2, CAMK2, MGC29528


Genbank Number:


References:


1. Tombes, R. M. et al: Identification of novel human tumor cell-specific CaMK-II variants. Biochim. Biophys. Acta 1355: 281-292, 1997.

2. Thiagarajan, T. C. Et al: Alpha- and beta-CaMKII: inverse regulation by neuronal activity and opposing effects on synaptic strength. Neuron 36: 1103-1114, 2002.


Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~58 kDa



Product Datasheets



Safety Datasheet



RESEARCH AREAS

Cardiovascular Disease, ERK/MAPK Pathway, Neurobiology, PKA/PKC Pathway, Ser/Thr Kinases


RELATED PRODUCTS


  CAMK1, Active, C07-10G

  CAMKK2, Active, C18-10G

  CAMK2 delta, Active, C13-10G

  Calmodulin 1 Protein, C01-30H


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