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KINASES - ANKK1 (SGK288), Active (A20-10G)

Product Name Catalog Number Pack Size Price(USD)  
ANKK1 (SGK288), Active A20-10G-05 5 ug $226 Add to Cart
ANKK1 (SGK288), Active A20-10G-10 10 ug $325 Add to Cart
ANKK1 (SGK288), Active A20-10G-BULK BULK Contact Us  


Description: Full-length recombinant human ANKK1 (SGK288) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Species: Human

Tag: GST tag

Expression System: Sf9 insect cells using baculovirus

Sequence: Full Length

Genbank Number: NM_178510    


Specific Activity : Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.



Purity : Sample Purity Data. For specific information on a given lot, see related technical data sheet.



Storage, Stability and Shipping : Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Applications : Kinase Assay, Western Blot

Molecular Weight : ~115 kDa

Gene Aliases : X-kinase, PKK2, SGK288

Scientific Background : ANKK1 or ankyrin repeat and kinase domain containing 1 is belongs to the Ser/Thr protein kinase family, and protein kinase superfamily that involved in signal transduction pathways (1). ANKK1 is closely linked to DRD2 gene on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene and it was determined to be located in exon 8 of ANKK1 gene where it causes a nonconservative amino acid substitution (2).

References :
1. Manning, G.et.al: The protein kinase complement of the human genome. Science 298: 1912-1934, 2002.

2. Neville, M. J.et.al: Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23.1. Hum. Mutat. 23: 540-545, 2004.

Product Sheets

SDS

Research Areas
Cancer, Neurobiology, Ser/Thr Kinases,

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