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MYO3 beta, Active

Recombinant human MYO3beta (1-326) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. M66-11G


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Catalog No. Pack Size Price (USD)
M66-11G-05 5 ug $226
M66-11G-10 10 ug $325
M66-11G-BULK BULK Contact Us  


Overview:

MYO3β is a member of the Class III myosins that are actin-dependent motor proteins containing an amino-terminal kinase domain. MYO3β contains a N-terminal kinase domain, followed by motor, neck, and tail domains. The MYO3β gene generates a variety of splice variants that contain 1 or 2 calmodulin-binding (IQ) motifs in the neck domain and 1 of 3 domains in the tail domain. Northern blot analysis shows expression of a 7-kb MYO3β transcript in the human retina but not in a RPE cell line (1). The MYO3β gene transcript is also detected in the kidney, intestine and testis. The MYO3β gene maps to chromosome 2q31.1-q31.2 by genomic sequence alignment.


Gene Alisases:

myosin IIIB


Genbank Number:


References:


1. Dose, A C. et al: A class III myosin expressed in the retina is a potential candidate for Bardet-Biedl syndrome. Genomics 79: 621-624, 2002.


Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~63 kDa



Product Datasheets



Safety Datasheet



There are no related publications available for this product.


RESEARCH AREAS

Neurobiology, Ser/Thr Kinases


RELATED PRODUCTS


  Kinase Assay Buffer I, K01-09


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