Home   >   Enzymes   >   Kinases

LCK, Active

Recombinant full-length human LCK was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
Catalog No. L03-10G

Shop Online

Catalog No. Pack Size Price (USD)
L03-10G-05 5 ug $226
L03-10G-10 10 ug $325
L03-10G-BULK BULK Contact Us  


LCK (p56lck) is a member of the src family of non-receptor tyrosine kinases. It was identified as a gene rearranged and overexpressed in the murine lymphoma LSTRA, most likely as a result of the insertion of Moloney murine leukemia virus DNA immediately adjacent to the gene (1). Lck behaves as a proto-oncogene and can lead to cell transformation upon activation. A number of human cancer cell lines show overexpression of LCK, pointing to a possible role for this kinase in the initiation and maintenance of the transformed state in human cancers (2).

Gene Alisases:

YT16, p56lck, pp58lck

Genbank Number:


1. Fischer, S. et al: The amino terminal region of the p56 lck from LSTRA exerts negative modulation on the tyrosine kinase activity. Biochem Biophys Res Commun. 1987 Mar 30;143(3):819-26.

2. Veillette, A. et al: Expression of the lck tyrosine kinase gene in human colon carcinoma and other non-lymphoid human tumor cell lines. Oncogene Res. 1987 Sep-Oct;1(4):357-74.

Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Molecular Weight:

~84 kDa

Product Datasheets

Safety Datasheet


Cancer, Cytoplasmic Tyrosine Kinases, Inflammation, JAK/STAT Pathway, NfkB Pathway


  HCK, Active, H02-11G

  LYN B, Active, L13-10G

  BTK, Active, B10-10H

  Poly (4:1 Glu, Tyr) Peptide, P61-58



Terms of Service

Privacy Policy

Get the latest resources, updates and offers in your inbox