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Name Catalog Number
2019-nCoV Spike protein RBD (R346K, E484K, N501Y) C19SD-G231NH
AsCas12a, Active CS12A-E311H
Protein A PA01-S551H
2019-nCoV Spike protein RBD (Y449H, E484K, N501Y) C19SD-G231PH
2019-nCoV Spike protein S1 (T95I, Y144T, Y145S, ins146N, R346K, E484K, N501Y, D614G, P681H) C19S1-G231MH
Asp f 9 AF09-A931H
Everolimus F17-901D
PD-325901 M02-901B
Ponatinib A03-900
Tofacitinib J01-900
2019-nCoV Delta Variant Neutralization ELISA Kit C19SD-ND887
2019-nCoV Spike protein RBD (Omicron) C19SD-G231OH
2019-nCoV Spike protein S1 (Omicron) C19S1-G231OH
Name Catalog Number
Name Catalog Number
2019-nCoV Spike protein RBD (Omicron) C19SD-G231OH
2019-nCoV Spike protein S1 (Omicron) C19S1-G231OH
Name Catalog Number
2019-nCoV Spike protein RBD (R346K, E484K, N501Y) C19SD-G231NH
AsCas12a, Active CS12A-E311H
Protein A PA01-S551H
2019-nCoV Spike protein RBD (Y449H, E484K, N501Y) C19SD-G231PH
2019-nCoV Spike protein S1 (T95I, Y144T, Y145S, ins146N, R346K, E484K, N501Y, D614G, P681H) C19S1-G231MH
Asp f 9 AF09-A931H
Everolimus F17-901D
PD-325901 M02-901B
Ponatinib A03-900
Tofacitinib J01-900
2019-nCoV Delta Variant Neutralization ELISA Kit C19SD-ND887
Name Catalog Number
Name Catalog Number
T4 UvsY Protein T4SY-C501H
NAE1 Protein N209-31H
NAE1/UBA3 Complex, Active U203-380G
Neddylation Buffer N01-09
2019-nCoV Spike protein S1 (T19R, G142D, del157-158, L452R, T478K, D614G, P681R) C19S1-G231LH
2019-nCoV Spike protein RBD (L452Q, F490S) C19SD-G231MH
2019-nCoV Spike protein S1 (T95I, G142D, E154K, L452R, E484Q, D614G, P681R) C19S1-G231KH
Name Catalog Number
LbuCas13a, Active CS13A-E322U
AapCas12b, Active C12B1-E311U
2019-nCoV Spike protein RBD, HRP conjugated C19SD-G241D
2019-nCoV Spike protein RBD (K417N, E484K, N501Y), HRP conjugated C19SD-G232D
2019-nCoV Spike protein RBD (K417T, E484K, N501Y), HRP conjugated C19SD-G231AD
2019-nCoV Spike protein RBD (L452R, E484Q), HRP conjugated C19SD-G231DD
2019-nCoV Spike protein RBD (L452R, T478K), HRP conjugated C19SD-G231FD
2019-nCoV Spike protein RBD (N501Y), HRP conjugated C19SD-G231D
T4 UvsX DNA Recombinase T4SX-E311U
T4 gp32 Protein T4G32-C501H
Bsu DNA Polymerase Large Fragment BD01-E311U
Sau DNA Polymerase Large Fragment SD01-E311U
DGKG, Active D25-10BH
DGKG, Active D25-10BG
DGKG, Active D25-11H
PLK4 (G95L), Active P44-12G

PRODUCT SCOOP

To support the advancement of the next generation of kinase-targeted therapeutic programs, SignalChem has developed over 50 clinically relevant active EGFR mutants, representing the most comprehensive list of this class of proteins in the industry. Epidermal Growth Factor Receptor (EGFR) is an important trans-membrane Receptor Tyrosine Kinase extensively recognized for the role it plays in Cancer. Mutations in the EGFR encoding gene can compromise its biological function resulting in deregulation of key cell-signaling pathways. These alterations are the driving agents in many cancers as non-small cell lung cancer, glioblastoma, and basal-like breast cancer.

Tyrosine kinase inhibitors, targeting critical EGFR mutations have revolutionized targeted therapeutics of multiple key cancers such as non-small cell lung cancer (NSCLC) and has established EGFR's as important drug targets. Furthermore, researchers are constantly being challenged by resistance to EGFR targeting cancer therapies, as a result, altering the clinical implications of these anti-EGFR treatments and drug discovery projects. To tackle these challenges, and aide the global life science community, SignalChem has utilized our protein kinase experts with over 100 years of combined experience in developing an effective line of biologically active recombinant EGFR mutants for the international research community.



Upcoming Events

Come chat with us at the following events:

AACR

New Orleans, USA
April 8-13, 2022

PEGS Boston

Boston, USA
May 11-13, 2022

BioEurope Spring

Basel, Switzerland
March 28-30, 2022

Bio US

San Diego, USA
June 13-16, 2022

Medlab Asia Pacific

Bangkok, Thailand
Oct 19-21, 2022

Discovery On Target

Boston, USA
Oct 17-20, 2022

Society for Neuroscience

San Diego, USA
Nov 12-16, 2022

Medica

Dusseldorf, Germany
Nov 14-18, 2022

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