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Name Catalog Number
Taq Plus Master Mix (Dye Plus) TQ02-E012
Taq Plus Master Mix TQ02-E011
CD19 Protein C19-35H
CDK6/CyclinD2 Protein C35-34G
CyclinM Protein C89-30G
EGFR (D770_N771insG), Active E10-132XG
ABL1 (Y245F Y412F), Active A03-12QH
ABL1 (Y245F), Active A03-12PH
HER2 (V956R), Active E27-12PH
LRRK2 (I1371V), Active L10-12JG
MYT1, Active M67-10H
p70S6Kb (C150T), Active R22-12G
EGFR (N771_P772insN), Active E10-132YG
EGFR (P772_H773insPR), Active E10-132ZG
EGFR (S768I), Active E10-122I3G
FGFR2 (M420I), Active F05-12SG
FGFR2 (N549K), Active F05-12NG
TccCas13a, Active CS13A-E314H
MYCN Protein M86-34G
PAK3, Active P04-18G
ROCK2, Active R11M-11H
WEE2, Active W06-18G
TDP43 Protein T74-34G
Tau-441 (216-391), Biotinylated T08-55LNB
Tau-361 Protein T09B-54N
RIPK1, Active R07D-112G
RIPK1, Active R07C-112G
RIPK1, Active R07D-11G
CyclinD2 Protein C81-30B2G
MET, Active M52-18H
KRAS (G12C) Protein R06-32DTH
NRAS (Q61K), Biotinylated R07-321HB
NRAS, Active R107-310AH
KRAS, Active (Biotinylated) R106-310HB
HRAS, Active (Biotinylated) R105-310HB
Alpha-synuclein, PLK2-phosphorylated S22-54H
MEF2A Protein M20-34G
EGFR (V774_C775insHV) Protein E10-13SG
EGFR (d746-750 T790M C797G) Protein E10-13TG
MYC Protein M86-30G
GSK3b (C199A), Active G09-12H
WDR48 Protein W298-31G
Peptide Dilution Buffer P58-09
2019-nCoV Spike protein S1 (L452R, E484Q, D614G, P681R) C19S1-G231EH
Pen ch 18 PC18-A961H
Name Catalog Number
Peptide Dilution Buffer P58-09
2019-nCoV Spike protein S1 (L452R, E484Q, D614G, P681R) C19S1-G231EH
Pen ch 18 PC18-A961H
Name Catalog Number
KRAS (G12C) Protein R06-32DTH
NRAS (Q61K), Biotinylated R07-321HB
NRAS, Active R107-310AH
KRAS, Active (Biotinylated) R106-310HB
HRAS, Active (Biotinylated) R105-310HB
Alpha-synuclein, PLK2-phosphorylated S22-54H
MEF2A Protein M20-34G
EGFR (V774_C775insHV) Protein E10-13SG
EGFR (d746-750 T790M C797G) Protein E10-13TG
MYC Protein M86-30G
GSK3b (C199A), Active G09-12H
WDR48 Protein W298-31G
Name Catalog Number
Taq Plus Master Mix (Dye Plus) TQ02-E012
Taq Plus Master Mix TQ02-E011
CD19 Protein C19-35H
CDK6/CyclinD2 Protein C35-34G
CyclinM Protein C89-30G
EGFR (D770_N771insG), Active E10-132XG
ABL1 (Y245F Y412F), Active A03-12QH
ABL1 (Y245F), Active A03-12PH
HER2 (V956R), Active E27-12PH
LRRK2 (I1371V), Active L10-12JG
MYT1, Active M67-10H
p70S6Kb (C150T), Active R22-12G
EGFR (N771_P772insN), Active E10-132YG
EGFR (P772_H773insPR), Active E10-132ZG
EGFR (S768I), Active E10-122I3G
FGFR2 (M420I), Active F05-12SG
FGFR2 (N549K), Active F05-12NG
TccCas13a, Active CS13A-E314H
MYCN Protein M86-34G
PAK3, Active P04-18G
ROCK2, Active R11M-11H
WEE2, Active W06-18G
TDP43 Protein T74-34G
Tau-441 (216-391), Biotinylated T08-55LNB
Tau-361 Protein T09B-54N
RIPK1, Active R07D-112G
RIPK1, Active R07C-112G
RIPK1, Active R07D-11G
CyclinD2 Protein C81-30B2G
MET, Active M52-18H
Name Catalog Number
Uracil-DNA Glycosylase (UDG) UG06-E311
Heat-labile UDG UG05-E311
M-MLV (H-) Reverse Transcriptase RTM01-E311
Murine RNase Inhibitor RNI01-G511
PureScript II Pro Reverse Transcriptase RTH02-E311
PureScript III Pro Reverse Transcriptase RTH03-E311
Taq Pro Universal SYBR qPCR Master Mix TQ03-E011
PDE12, Active P100-310G
ROS1(L2086F), Active R14-12CG
Name Catalog Number
Streptavidin ST01-E511U
Streptavidin ST01-E511H
HRAS (G12A) Protein R05-32ATH
HRAS (G12C) Protein R05-32CTH
HRAS (G12S) Protein R05-32STH
HRAS (G12V) Protein R05-32VTH
KRAS (G12C) Protein R06-32DU
KRAS (G12D, Isoform B) Protein R06B-32BH
KRAS (G12D, Isoform B) Protein R06B-321BH
KRAS (Isoform B), Active R106B-311H
KRAS (Mature form, Isoform B), Active R106B-31H
NRAS, Active (Biotinylated) R107-31HB
NRAS, Active (Biotinylated) R107-311HB
NRAS (G12C) Protein R07-32CH
NRAS (Q61K) Protein R07-32H
NRAS (Q61K) Protein R07-321H
NRAS (Q61K), Biotinylated R07-32HB
NRAS, Active R107-311H
ABL1 (K290R) Protein A03-16NG
EGFR (V948R), Active E10-122H3H
FGFR2 (C491A V564I), Active F05-12PG
FGFR2 (C491A V564L), Active F05-12QG
FGFR2 (V564I), Active F05-12RG
HDAC6, Active H88M-30G
HDAC6, Active H88A-30G
HDAC6, Active H88D-30G
HDAC6, Active H88C-30G
HDAC11, Active H93D-30G
HDAC11, Active H93C-30G
HDAC11, Active H93M-30G
HDAC11, Active H93A-30G
HER3 (E928G) Protein E28-32AG
HER3 Protein E28-35G
HER3 Protein E28-35H
PI3K (p110 alpha (E545K)/p85 alpha), Active P27-152G
PI3K (p110 alpha(H1047R)/p85 alpha), Active P27-122EH
Bst II Pro DNA Polymerase Large Fragment BP01-E311
Name Catalog Number
ALK2, Active A06M-11G
c-KIT (d557-558 V654A), Active K06-12B2G
c-KIT (d557-558 Y823D), Active K06-12A2G
DDR2, Active D06M-11BG
FGFR2 (C491S V564L), Active F05-12MG
FGFR2 (E565A), Active F05-12KG
FGFR2 (V564L), Active F05-12LG
FLT3 (F691L D835Y), Active F12-12KG
c-KIT (d560-576 Y823D), Active K06-12YG
FLT3 (Y591-V592insVDFREYEYD D835Y), Active F12-12JG
FLT3 (Y591-V592insVDFREYEYD F691L), Active F12-12LG
PLK3, Active P43-13H
RET (Y806C), Active R02-12SG
RET (Y806N), Active R02-12TG
Alpha Synuclein Antibody (pSer129) S22-635R
Alpha Synuclein Antibody (pSer129), J18 S22-65R
Alpha Synuclein Antibody S22-62R
Alpha Synuclein Antibody, 3C11 S22-61M
Alpha Synuclein Antibody, 3F8 S22-61CM
Alpha Synuclein Antibody, 4F1 S22-61DM
Alpha Synuclein Antibody, 10H7 S22-61BM
Tau Antibody (pSer202/pThr205), AH36 T08-65R
Tau Antibody T08-62BR
Tau Antibody T08-63R
Tau Antibody, 1D5 T08-60M
Tau Antibody, 3D4 T08-60BM
Alpha Synuclein (A53T) Pre-Formed Fibrils (Type 1) S22-361N
Alpha Synuclein (A53T) Protein S22-36N
Alpha Synuclein Pre-Formed Fibril (Type 1) S22-381N
Alpha Synuclein Pre-Formed Fibril (Type 1) S22M-381N
Alpha synuclein Pre-Formed Fibril (Type 2) S22-382N
Alpha Synuclein Protein Monomer (Type 1) S22-371N
Alpha-synuclein Protein Monomer (Type 2) S22-372N
Alpha Synuclein Protein Monomer S22M-37N
Amyloid Beta Peptide (1-42) A42-58
Tau K18 (P61L) Protein Monomer T18-57GN
Tau K18 (P61L) Pre-Formed Fibril T18-58GN
Tau-441 (P301S) Pre-Formed Fibril T08-58GN
Tau-441 (P301S) Protein Monomer T08-57GN
Tau Antibody T08-62R

PRODUCT SCOOP

To support the advancement of the next generation of kinase-targeted therapeutic programs, SignalChem has developed over 50 clinically relevant active EGFR mutants, representing the most comprehensive list of this class of proteins in the industry. Epidermal Growth Factor Receptor (EGFR) is an important trans-membrane Receptor Tyrosine Kinase extensively recognized for the role it plays in Cancer. Mutations in the EGFR encoding gene can compromise its biological function resulting in deregulation of key cell-signaling pathways. These alterations are the driving agents in many cancers as non-small cell lung cancer, glioblastoma, and basal-like breast cancer.

Tyrosine kinase inhibitors, targeting critical EGFR mutations have revolutionized targeted therapeutics of multiple key cancers such as non-small cell lung cancer (NSCLC) and has established EGFR's as important drug targets. Furthermore, researchers are constantly being challenged by resistance to EGFR targeting cancer therapies, as a result, altering the clinical implications of these anti-EGFR treatments and drug discovery projects. To tackle these challenges, and aide the global life science community, SignalChem has utilized our protein kinase experts with over 100 years of combined experience in developing an effective line of biologically active recombinant EGFR mutants for the international research community.



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Orlando, Florida, USA
April 14-19, 2023

AACC

California, USA
July 23-27. 2023

ICBPS

Vancouver, Canada
August 03-04, 2023

ICLST

Vancouver, Canada
September 23-24, 2023

Discovery on Target

Boston, USA
September 25-28, 2023

Medica

Dusseldorf, Germany
November 13-16, 2023

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